CD38 is an enzyme with NAD-depleting and intracellular signaling activity expressed on the cell surface, in intracellular compartments and in mitochondria, and is linked to inflammatory and autoimmune ...
The University of Michigan John Varga Lab, in collaboration with the Mayo Clinic and Northwestern researchers, published an article last year suggesting that a heavy-chain monoclonal antibody, Ab68, ...
Scleroderma is a chronic autoimmune disease of women. Over time, people living with scleroderma develop progressive and irreversible scarring. Scarring, called fibrosis, effects the lungs, heart and ...
The Transcreener ® ADPR Assay is a biochemical HTS test that quantitatively measures the production of ADP-ribose (ADPR) in enzymatic processes. The assay employs a coupling enzyme to transform ADPR ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Nura Bio Inc., a biopharma company based in South San Francisco, focused on the discovery and development of disease-modifying neuroprotective drugs, ...
COPENHAGEN, Denmark--(BUSINESS WIRE)-- Genmab A/S (Nasdaq: GMAB) announced today that Johnson & Johnson (J&J) has decided that it will not exercise its option to receive a worldwide license to develop ...