In the embryonic kidney, three types of precursor cells interact with each other to form a three-dimensional structure. Previous studies successfully induced nephron structures via nephron progenitors ...

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a ...

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a ...

Researchers have created what could be a key building block for assembling a synthetic kidney. They describe how they generate rudimentary kidney structures, known as organoids, that resemble the ...

Chronic kidney disease affects 1 in 9 Americans and more than 300 million persons worldwide. Of these millions, approximately 2.5% have end-stage kidney failure and require treatment with dialysis or ...

Tolvaptan is a vasopressin receptor antagonist. Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron. Blocking ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...

In the embryonic kidney, three types of precursor cells, nephron progenitor cells, ureteric buds, and interstitial progenitor cells, interact to form three-dimensional structures of the kidney.