Alcohol use disorder (AUD) is one of the leading causes of preventable death in the United States and worldwide, and leads to substantial disease and medical complications. While treatments are ...

Research on the biological basis of addiction published in Biological Psychiatry uncovers the critical role that the HDAC5 enzyme plays in gene expression in the brain's epigenetic mechanisms that ...

John F. Kelly, PhD, of the Recovery Research Institute and Department of Psychiatry at Mass General Brigham, is the lead author of a paper published in Frontiers in Public Health , "Long-term relapse: ...

For the budding alcoholic/addict in recovery, relapse is all too often a nano second away. Even for the well seasoned soul who has practiced a clean and sober lifestyle for many years, relapse may be ...

John F. Kelly, PhD , of the Recovery Research Institute and Department of Psychiatry at Mass General Brigham, is the lead author of a paper ...

Relapse isn’t a failure. It’s a signal. It tells us that something deeper is still driving our old behaviors. For decades, I’ve studied the science of addiction, relapse, and behavior change through ...

A common drug used for inflammatory skin conditions may hold the key to treating both alcohol addiction and pain sensitivity. That’s what scientists at a leading research institute have found. In a ...