Dendritic cell receptors, in particular C‐type lectins such as DC-SIGN, play a pivotal role in the immune response by recognising and internalising diverse glycan structures present on pathogens. The ...

When the liver is injured - for example, due to bile accumulation - immune cells become activated. In mouse experiments, the ...

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

A new metabolic mechanism describes how tumors disable “gatekeeper” cells to prevent immune response to cancer.

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria ...

Innate immunity is a cornerstone of the body’s immediate defense against cancer, orchestrating the early recognition and response to tumor cells through key ...

Chemokines, acting as "traffic controllers" in the tumor microenvironment, regulate immune cell infiltration and local ...

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment ...