The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate ...

Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

Easy-to-use epigenetic editors like CRISPRoff have tremendous therapeutic potential, in large part because, like the genome, the epigenome can be inherited. When CRISPRoff silences a gene, not only ...

Epigenetics refers to how your behaviors and environment can cause changes that affect the way your genes work, according to the Centers for Disease Control and Prevention. Unlike genetic changes or ...

EPFL scientists have identified a molecular pathway that protects cells from lipid oxidation and ferroptosis, a regulated ...

Epigenetic editing is a promising method for gene regulation in vitro and in vivo, allowing precise control of gene expression without altering the DNA sequence, thereby minimizing genotoxic risks.

Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated. The ...

(Nanowerk News) Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that ...