Background: The clinical evidence base for ototoxicity and nephrotoxicity outcomes with once-daily dosing (ODD) of gentamicin in children is suboptimal. Therapeutic drug monitoring (TDM) in once-daily ...

To examine the impact of a change in the empiric gentamicin dose from 5 mg kg −1 every 24 h (Q24 h period) to 5 mg kg every 36 h (Q36 h period) on target drug concentration achievement in neonates ...

Government has warned that gentamicin, an antibiotic drug used to treat several types of bacterial infections, could result in hearing loss. Government has warned that gentamicin, an antibiotic drug ...

Aminoglycoside exposure is a common cause of acute kidney injury (AKI). Delay in the diagnosis of AKI using conventional biomarkers has been one of the important obstacles in applying early effective ...

Kidney Failure Risk, Ammonia Excretion Linked These factors include a history of heart failure, which was associated with 3-fold increased odds of acute kidney injury. A history of heart failure is ...

We received an enquiry from an NHS microbiologist about a lack of recommendations in the NICE guideline about when to start treatment with neonatal gentamicin for suspected sepsis if the neonate has ...