Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...
Proteins possess diverse conformations, some pivotal in disease pathology. Protein misfolding and aggregation are linked to neurodegenerative conditions like Alzheimer's, Parkinson’s, and Huntington’s ...
Protein barcodes are short, information- rich stretches of amino acids encoded by DNA sequences that can be added to the DNA sequences coding for proteins. Then, when protein barcode DNA and protein ...
Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...
Quantum-Si’s New Preprint Showcases Protein Barcoding as a Powerful Tool for Transforming Proteomics
BRANFORD, Conn.--(BUSINESS WIRE)-- Quantum-Si Incorporated (QSI) (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company ...
Researchers at ESPCI Paris and Quantum-Si (QSI) demonstrate scalable platform for parallel binding kinetics and sequencing in new preprint The process works by tagging protein variants, such as ...
Barcoding technologies using the high information content encoded in oligonucleotide sequences have aided various applications in biotechnology, especially when paired with next-generation DNA ...
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