The human body is naturally equipped with defenses to fight off viral infections. For a virus to successfully infect it, it must first overcome these defenses. To do so, viruses have evolved ...
Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...
ITCH is an important regulator of SARS-CoV-2 life cycle, coordinating ubiquitination, assembly, autophagosome-mediated secretion, and spike stability, highlighting ITCH as a promising therapeutic ...
The spike glycoprotein of SARS-CoV-2 undergoes intricate conformational changes that govern receptor engagement, immune recognition and membrane fusion. Variants of concern (VOCs) harbour amino acid ...
Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still ...
New study reveals how lingering spike protein in the brain's borders could explain long-term COVID-19 neurological symptoms and highlight vaccines' protective role. Study: Persistence of spike protein ...
The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...
Decisions made by researchers during the microliter, benchtop development of biotherapeutics made from monoclonal antibodies (mAb) and recombinant proteins often don’t scale to larger stirred tank ...
Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement ...
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