A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...
Advancements in HIV/AIDS research, drug development, and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check ...
The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...
In individuals who started antiretroviral therapy during acute HIV infection, the proliferative capacity of HIV-specific CD8+ ...
A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the first year of antiretroviral therapy. Although there can be laboratory ...
*Adjusted model includes: age, sex, race/ethnicity, year of diagnosis, Deyo comorbidity index, smoking, alcohol abuse, time-dependent treatment, and organization. † Hazard ratios significant at a ...
CD4 tests are strongly recommended as the preferred method to identify advanced HIV disease among people living with HIV, the World Health Organization (WHO) has strongly recommended in its 2025 ...