Tumor-suppressive miRNAs inhibit oncogenic pathways, preventing cancer progression, while oncogenic miRNAs promote tumor growth by targeting tumor suppressor genes. miRNA, microRNA. Lung cancer (LC) ...
The phase 3 KANDLELIT-007 trial (NCT07190248) evaluating the KRAS G12C inhibitor calderasib (MK-1084) plus subcutaneous pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex; SC pembrolizumab) ...
Researchers uncover a cunning new trick by which breast cancer cells evade immune attack. While the cGAS-STING pathway normally detects cytosolic DNA and activates anti-tumor immunity via ...