Perineural invasion (PNI) is a new approach of cervical cancer invasion and metastasis, involving the cross-talk between tumor and nerve. However, the initiating signals and cellular interaction ...

Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves ...

Metastasis is the primary cause of mortality in cancer patients. Despite being at an early stage, patients with pancreatic ductal adenocarcinoma (PDAC) experience a substantial rate of postoperative ...

A new Brazilian study has revealed the key role of the protein periostin and stellate pancreatic cells in allowing pancreatic cancer to infiltrate nerves and spread early, increasing the risk of ...

It's common for healthcare professionals to order biopsies for patients whom they suspect may have prostate cancer. A biopsy ...

The presence of perineural invasion in a prostate biopsy has important implications for active surveillance. Perineural invasion detected on biopsy in patients on active surveillance for low-risk ...

The specific course of treatment depends on the extent of spread, the type of tumor, and its location. Perineural invasion (PNI) describes the phenomenon where cancer cells invade the perineural space ...

Expert Rev Anticancer Ther. 2012;12(3):359-371. An example of the definition of radiotherapy target volumes in a patient with a parotid gland tumor with PNS is illustrated in Figure 12. 1 Department ...

Medullary-Type Poorly Differentiated Adenocarcinoma of the Large Bowel: A Distinct Clinicopathologic Entity Characterized by Microsatellite Instability and Improved Survival PURPOSE: The reasons for ...

Tumors do not communicate only with immune cells, blood vessels, and stromal tissue. A growing body of evidence suggests that cancer can also co-opt the nervous system, reshaping the tumor ...

Please provide your email address to receive an email when new articles are posted on . Only the involvement of five or more distinct nerves was associated with poor patient outcomes. Poor outcomes ...