Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Panelists discuss how ARNIs like sacubitril-valsartan provide superior outcomes compared with ACE inhibitors in HFrEF (20% reduction in cardiovascular events, 16% mortality reduction), with broad FDA ...

Finerenone's approval by the FDA to treat type 2 diabetes–associated chronic kidney disease was supported by data from the phase 2 FIDELIO-DKD trial; now, the results of FINEARTS-HF show real-world ...

When the heart struggles to pump efficiently, a cascade of events unfolds. Fluid accumulates in the lungs and extremities. Breathing becomes labored. Simple activities like climbing stairs or carrying ...

Credit: Getty Images A 65-year-old woman presents to her primary care provider with a chief complaint of "feeling winded" for the last 3 weeks. A 65-year-old woman presents to her primary care ...