Researchers at Tulane University have identified a previously unknown mechanism that activates pain signaling in the nervous system, a discovery that could reshape future drug development and offer ...

Researchers at the Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, together with collaborators from ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Summary: Researchers have identified a specific signaling mechanism in brain immune cells that regulates anxiety and grooming ...

In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers have discovered a biological mechanism that makes plant roots more welcoming to beneficial soil microbes. Researchers have discovered a biological mechanism that makes plant roots more ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...