Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering ...

Researchers at the University of Southampton engineered four-pronged antibodies that cluster the CD27 immune receptor, ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

A new approach to strengthening the immune system's fight against cancer is showing potential. Researchers at the University ...

Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.

Researchers at the University of Southampton have developed a new antibody design that boosts the immune system’s ability to fight cancer by enhancing activation of T cells through the CD27 receptor.

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them-and how silencing that signal could revive the body's immunity. The study led by Weill ...