In the few years since the introduction of peptide nucleic acid, or PNA (P.E. Ni et al., Science 254:1497-1500, 1991)-a nucleic acid analog with a peptide rather than sugar-phosphate backbone-no less ...
Cyclic peptides offer enhanced stability and bioavailability, but precise cyclization strategies and specialized synthetic techniques are required to maintain their biological activity. A recent ...
A team at ETH Zurich developed a new peptide-based organocatalyst that handles macrocycle formation from start to finish. Macrocyclic compounds are ubiquitous both in nature and in the chemical ...
Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...
This photo shows a novel, bimodal peptide nucleic acid (PNA) analog that’s in the process of crystallizing. Rajat HS, a PhD candidate at the Indian Institute of Science Education and Research, ...
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